{"id":1217,"date":"2018-07-19T18:45:21","date_gmt":"2018-07-19T10:45:21","guid":{"rendered":"http:\/\/baopie.doctor.binflux.com\/2018\/07\/19\/%e5%a9%a6%e5%a5%b3amh%e6%a5%b5%e4%bd%8e%e7%9a%84%e6%b4%bb%e7%94%a2%e6%a9%9f%e6%9c%83\/"},"modified":"2018-07-19T18:45:21","modified_gmt":"2018-07-19T10:45:21","slug":"%e5%a9%a6%e5%a5%b3amh%e6%a5%b5%e4%bd%8e%e7%9a%84%e6%b4%bb%e7%94%a2%e6%a9%9f%e6%9c%83","status":"publish","type":"post","link":"https:\/\/www.becphd.pro\/?p=1217","title":{"rendered":"\u5a66\u5973AMH\u6975\u4f4e\u7684\u6d3b\u7522\u6a5f\u6703"},"content":{"rendered":"

\u7ffb\u81ea\u6b0a\u5a01\u7684\u751f\u6b96\u671f\u520aHUMAN REPRODUCTION<\/span><\/strong><\/p>\n

\u00a0<\/p>\n

2011.04.30<\/strong><\/span><\/p>\n

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\u5967\u5730\u5229\u7684\u7814\u7a76<\/strong><\/span><\/p>\n

\u00a0<\/p>\n

\u5a66\u5973AMH\u6975\u4f4e\u7684\u6d3b\u7522\u6a5f\u6703<\/span><\/strong><\/p>\n

\u00a0<\/p>\n

\u6458\u8981<\/span><\/strong><\/p>\n


\u80cc\u666f:<\/strong><\/span><\/p>\n

\u7814\u7a76\u5a66\u5973\u6975\u4f4e\u7684<\/span>AMH<\/span>\uff08<\/span><0.1-0.4<\/span>\u00a0ng\/ml<\/span>\uff09\u5728\u4eba\u5de5\u751f\u6b96\u7684\u6cbb\u7642\u5f8c\u6d3b\u7522\u7684\u80fd\u529b\u8207\u9019\u6a23\u7684\u80fd\u529b\u662f\u5426\u8207\u5e74\u9f61\u6709\u95dc\u3002<\/span><\/p>\n

\u00a0<\/p>\n

\u65b9\u6cd5:<\/span><\/strong><\/p>\n

2006<\/span>\u5e74<\/span>1<\/span>\u6708\u81f3<\/span>2009<\/span>\u5e74<\/span>10<\/span>\u6708\u9023\u7e8c<\/span>\u00a0128<\/span>\u4f8b<\/span>AMH\u00a0<\/span>\u2264<\/span>0.4<\/span>\u00a0ng\/ml<\/span>\u7684\u60a3\u8005\u63a5\u53d7<\/span>IVF<\/span>\u6cbb\u7642\u9032\u884c\u56de\u9867\u6027\u7684\u7814\u7a76\u61f7\u5b55\u7387\u548c\u6d3b\u7522\u7684\u6a5f\u6703\u3002<\/span><\/span><\/p>\n

\u00a0<\/p>\n

\u7d50\u679c:<\/span><\/strong><\/p>\n

\u60a3\u8005\u63d0\u51fa\u4e86\u5728\u5e73\u5747\uff08<\/span>\u00b1<\/span>\u6a19\u6e96\u5dee\uff09\u5e74\u9f61\u70ba<\/span>\u00a040.8 \u00b1 4.1<\/span>\u6b72\uff0c\u5e73\u5747\uff08<\/span>\u00b1<\/span>\u6a19\u6e96\u5dee\uff09<\/span>FSH<\/span>\u70ba15.7 \u00b1 11.1 mIU \/ ml<\/span>\uff0c<\/span>\u4e14\u5e73\u5747\uff08<\/span>\u00b1<\/span>\u6a19\u6e96\u5dee\uff09<\/span>AMH<\/span>\u70ba<\/span>\u00a00.2 \u00b1 0.1<\/span>\u00a0ng\/ml<\/span>\u3002\u4e00\u767e\u4e8c\u5341\u540d\u5a66\u5973\u9032\u884c\u4e86\u7e3d\u5171\u63a5\u53d7\u4e86<\/span>254<\/span>\u500b<\/span>IVF<\/span>\u9031\u671f\u3002\u5171<\/span>20<\/span>\u500b<\/span>IVF<\/span>\u9031\u671f\u6709\u81e8\u5e8a\u61f7\u5b55\uff08<\/span>7.9<\/span>\uff05\u6bcf\u9031\u671f\u7684\u958b\u59cb<\/span>\u00a0[95<\/span>\uff05\u53ef\u4fe1\u5340\u9593\uff08<\/span>CI<\/span>\uff09\uff1a<\/span>4.9-11.9<\/span>\uff05<\/span>]; 15.6<\/span>\uff05\u7684\u7d2f\u7a4d<\/span>\u00a0[<\/span>\u5340\u9593\uff1a<\/span>9.8-23.1<\/span>\uff05<\/span>]<\/span>\uff09\u300220<\/span>\u500b\u5a66\u5973\u9a57\u5b55\u6210\u529f(clinical pregnancy)<\/span>\uff0c\u6709<\/span>12<\/span>\u540d\u61f7\u5b55\u5a66\u5973\uff08\u5373<\/span>11<\/span>\u500b\u55ae\u80de\u80ce\u548c\u4e00\u5c0d\u96d9\u80de\u80ce\uff09\u5171\u7522\u4e0b<\/span>13<\/span>\u500b\u6d3b\u7522\u5b30\u5152\u548c<\/span>8<\/span>\u4f8b\u61f7\u5b55\u5a66\u5973\u6d41\u7522\u3002<\/span>8<\/span>\u4f4d\u751f\u7522\u662f\u7b2c\u4e00\u500b<\/span>IVF<\/span>\u9031\u671f\uff08\u6bcf\u9031\u671f\u958b\u59cb<\/span>\u00a06.3<\/span>\uff05\uff09\u548c<\/span>4<\/span>\u500b\u751f\u7522\u5728\u96a8\u5f8c\u7684<\/span>IVF<\/span>\u9031\u671f\uff08<\/span>3.2<\/span>\uff05\uff09\u3002\u4f9d\u5973\u6027\u7684\u5e74\u9f61\u8a08\u7b97\uff0c<\/span>70<\/span>\u540d\u5a66\u5973<\/span>\u2264<\/span>42<\/span>\u6b72\u5171\u6709<\/span>16<\/span>\u500b\u81e8\u5e8a\u598a\u5a20\u61f7\u5b55\uff0c\u800c\u5176\u4e2d<\/span>10<\/span>\u4f8b\uff08<\/span>14.3<\/span>\uff05\uff09\u6d3b\u7522\uff0c\u800c<\/span>58<\/span>\u4f8b<\/span>>42<\/span>\u6b72\u6709<\/span>4<\/span>\u500b\u81e8\u5e8a\u61f7\u5b55\uff0c\u5176\u4e2d<\/span>2<\/span>\u4f8b\u6d3b\u7522\uff08<\/span>3.4<\/span>\uff05\uff09\uff0c\u76f8\u8f03\u65bc\u5c0f\u65bc<\/span>42<\/span>\u6b72\u7684\u65cf\u7fa4\u986f\u8457\u6e1b\u5c11\u61f7\u5b55\u7684\u6a5f\u6703\uff08<\/span>P = 0.013<\/span>\uff09\u548c\u751f\u7522\u7387\uff08<\/span>P = 0.036<\/span>\uff09\u3002<\/span><\/p>\n

\u00a0<\/p>\n

\u7d50\u8ad6:<\/span><\/strong><\/p>\n

\u6975\u4f4e\u7684<\/span>AMH<\/span>\uff0c\u4e2d\u7b49\u4f46\u5408\u7406\u7684\u61f7\u5b55\u7387\u548c\u6d3b\u7522\u7387\u4ecd\u7136\u662f\u53ef\u80fd\u7684\u3002\u6975\u4f4e\u7684<\/span>AMH<\/span>\u4e26\u4e0d\u80fd\u4ee3\u8868\u552f\u4e00\u7684\u6307\u6a19\u800c\u66ab\u7de9\u751f\u80b2\u6cbb\u7642\u3002<\/span><\/p>\n

\u00a0<\/p>\n

\u539f\u6587<\/span><\/p>\n

\u00a0<\/p>\n

Hum Reprod. 2011 Apr 30.<\/span><\/p>\n

\u00a0<\/p>\n

Live birth chances in women with extremely low-serum anti-Mullerian hormone levels.<\/strong><\/span><\/p>\n

Weghofer A<\/span><\/a>,\u00a0Dietrich W<\/span><\/a>,\u00a0Barad DH<\/span><\/a>,\u00a0Gleicher N<\/span><\/a>.<\/span><\/p>\n

Source<\/strong><\/span><\/p>\n

Department of Obstetrics and Gynecology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.<\/span><\/p>\n

Abstract<\/strong><\/span><\/p>\n

BACKGROUND To determine whether women with extremely low-serum anti-Mullerian hormone (AMH) levels (<0.1-0.4 ng\/ml) still demonstrate live birth potential with assisted reproduction and whether such potential is age dependent. METHODS Between January 2006 and October 2009, 128 consecutive infertility patients with AMH \u22640.4 ng\/ml were retrospectively evaluated for pregnancy chances and live birth rates after IVF. RESULTS Patients presented at a mean (\u00b1SD) age of 40.8 \u00b1 4.1 years, with mean (\u00b1SD) baseline FSH of 15.7 \u00b1 11.1 mIU\/ml and mean (\u00b1SD) AMH of 0.2 \u00b1 0.1 ng\/ml. One hundred and twenty-eight women underwent a total of 254 IVF cycles. Twenty clinical pregnancies were recorded (7.9% per cycle start [95% confidence interval (CI): 4.9-11.9%]; 15.6% cumulative [CI: 9.8-23.1%]). These pregnancies resulted in 13 live births in 12 women (i.e. 11 singletons and a pair of twins) and 8 patients miscarried. Eight deliveries occurred after the first cycle (6.3% per cycle start) and four after subsequent IVF cycles (3.2%). When evaluated according to female age, 70 women \u226442 years presented with 16 clinical pregnancies that resulted in 10 deliveries (14.3%), while 58 patients >42 years presented with four clinical pregnancies that resulted in 2 deliveries (3.4%), representing a reduced pregnancy chance (P = 0.013) and delivery rate (P = 0.036) versus age \u226442 years. CONCLUSIONS With extremely low-serum AMH levels, moderate, but reasonable pregnancy and live birth rates are still possible. Extremely low AMH levels do not seem to represent an appropriate marker for withholding fertility treatment.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

\u7ffb\u81ea\u6b0a\u5a01\u7684\u751f\u6b96\u671f\u520aHUMAN REPRODUCTION \u00a0 2011.04.30 \u00a0 \u5967\u5730\u5229\u7684\u7814\u7a76 \u00a0 \u5a66\u5973A […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1217","post","type-post","status-publish","format-standard","hentry","category-know-how"],"_links":{"self":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1217","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1217"}],"version-history":[{"count":0,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1217\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1217"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1217"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1217"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}