{"id":1224,"date":"2018-07-19T18:45:22","date_gmt":"2018-07-19T10:45:22","guid":{"rendered":"http:\/\/baopie.doctor.binflux.com\/2018\/07\/19\/%e5%be%8c%e4%bb%a3%e7%9a%84%e6%80%a7%e5%88%a5%e6%af%94%e4%be%8b%e6%98%af%e8%88%87%e6%af%8d%e8%a6%aa%e6%9c%88%e7%b6%93%e5%88%9d%e6%bd%ae%e7%9a%84%e5%b9%b4%e9%bd%a1%e6%9c%89%e9%97%9c\/"},"modified":"2018-07-19T18:45:22","modified_gmt":"2018-07-19T10:45:22","slug":"%e5%be%8c%e4%bb%a3%e7%9a%84%e6%80%a7%e5%88%a5%e6%af%94%e4%be%8b%e6%98%af%e8%88%87%e6%af%8d%e8%a6%aa%e6%9c%88%e7%b6%93%e5%88%9d%e6%bd%ae%e7%9a%84%e5%b9%b4%e9%bd%a1%e6%9c%89%e9%97%9c","status":"publish","type":"post","link":"https:\/\/www.becphd.pro\/?p=1224","title":{"rendered":"\u5f8c\u4ee3\u7684\u6027\u5225\u6bd4\u4f8b\u662f\u8207\u6bcd\u89aa\u6708\u7d93\u521d\u6f6e\u7684\u5e74\u9f61\u6709\u95dc"},"content":{"rendered":"<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21467205##\" title=\"Human reproduction (Oxford, England).\" style=\"color: #008db0;\"><span style=\"color: #6000bf;\"><strong>Hum Reprod.<\/strong><\/span><\/a><span style=\"color: #6000bf;\"><strong>\u00a02011 Jun;26(6):1551-4. Epub 2011 Apr 5. (<\/strong><\/span><\/span><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\"><span style=\"color: #6000bf;\"><strong>\u6436\u9bae\u7248<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span><\/strong><\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u4f86\u81ea\u65e5\u672c\u7684\u7814\u7a76<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; vertical-align: top; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 18pt; color: maroon; font-family: \u6a19\u6977\u9ad4;\">\u5f8c\u4ee3\u7684\u6027\u5225\u6bd4\u4f8b\u662f\u8207\u6bcd\u89aa\u6708\u7d93\u521d\u6f6e\u7684\u5e74\u9f61\u6709\u95dc\u00a0<span style=\"word-break: break-all; background-color: #ebeff9; background-position: initial initial; background-repeat: initial initial;\" lang=\"EN-US\"><\/p>\n<p><\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u6458\u8981<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\"><br \/>\u00a0<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u63d0\u524d\u6708\u7d93\u521d\u6f6e<span style=\"word-break: break-all;\" lang=\"EN-US\">(<\/span>\u521d\u7d93<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span>\u7684\u5e74\u9f61\u662f\u4e73\u764c\u548c\u5375\u5de2\u764c\u7684\u5371\u96aa\u56e0\u7d20\uff0c\u4e5f\u8207\u589e\u52a0\u81ea\u7136\u6d41\u7522\u7387\u3002<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u76ee\u7684<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u662f\u63a2\u8a0e\u662f\u5426\u6709\u65e9\u671f\u6708\u7d93\u521d\u6f6e\u5e74\u9f61\u4e4b\u9593\u548c\u5f8c\u4ee3\u7684\u6027\u5225\u6bd4\u4f8b\u7684\u95dc\u806f\u3002<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u65b9\u6cd5<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u6211\u5011\u8a18\u9304\u4e86<span style=\"word-break: break-all;\" lang=\"EN-US\">10 847<\/span>\u505c\u7d93\u524d\u5a66\u5973<span style=\"word-break: break-all;\" lang=\"EN-US\">(<\/span>\u5e73\u5747\u51fa\u5e2d\u5e74\u9f61\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">37.5 \u00b1 7.2<\/span>\u6b72\uff0c\u7bc4\u570d<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a022-54<\/span>\u6b72\uff09\u5171\u751f\u51fa<span style=\"word-break: break-all;\" lang=\"EN-US\">21208<\/span>\u6d3b\u7522\u51fa\u751f\u5b30\u5152\u7684\u6027\u5225\uff0c\u53c3\u52a0\u4e86\u6211\u5011\u7684\u7522\u79d1\u548c\u5a66\u79d1\u8a3a\u6240\u7684\u8a55\u4f30\u3002<\/span><\/span><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; background-color: #ebeff9; font-family: \u6a19\u6977\u9ad4;\">\u6211\u5011\u8a08\u7b97\u7684\u65b0\u751f\u5152\u6027\u5225\u6bd4\u4f8b\u76f8\u5c0d\u65bc\u6bcd\u89aa\u7684\u6708\u7d93\u521d\u6f6e\u5e74\u9f61\uff08\u5f9e<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a09<\/span>\u5230<span style=\"word-break: break-all;\" lang=\"EN-US\">18<\/span>\u6b72\uff09\uff0c\u5411\u6bcf\u540d\u5a66\u5973\u751f\u80b2\u7684\u5b30\u5152\u6578\uff08\u5373\u751f\u80b2\u6307\u6578\uff09\u3002<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u7d50\u679c<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u89c0\u5bdf\u6bcd\u89aa\u8ab0\u9032\u5165\u521d\u6f6e\u5e74\u9f61\u5728<span style=\"word-break: break-all;\" lang=\"EN-US\">9<\/span>\u6b72<span style=\"word-break: break-all;\" lang=\"EN-US\">;<\/span>\u7684\u6bd4\u503c\u6bd4\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">OR<\/span>\uff09\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">95<\/span>\uff05\u7f6e\u4fe1\u5340\u9593\uff09\u76f8\u6bd4\uff0c\u6709\u4f4e\u5f8c\u4ee3\u7684\u6027\u5225\u6bd4\u4f8b\uff08\u7537<span style=\"word-break: break-all;\" lang=\"EN-US\">\/<\/span>\u5973\uff09\u7684<span style=\"word-break: break-all;\" lang=\"EN-US\">0.800(<\/span>\u5973\u591a\u7537\u5c11<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span>\uff0c\u90a3\u4e9b\u8207\u5c0d\u7167\u7d44<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a014<\/span>\u6b72\u521d\u6f6e\u70ba<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a00.72<\/span>\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">0.29-1.79<\/span>\uff09\u3002\u5728\u6027\u5225\u6bd4\u4f8b\u4ecd\u7136\u5f88\u4f4e\uff0c\u76f4\u5230\u8a72\u7d44\u7684\u6bcd\u89aa\u8ab0\u9032\u5165\u521d\u6f6e\u5728<span style=\"word-break: break-all;\" lang=\"EN-US\">12<\/span>\u6b72<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0[1.009<\/span>\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">OR<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">0.90<\/span>\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">0.85-0.95<\/span>\uff09<span style=\"word-break: break-all;\" lang=\"EN-US\">]<\/span>\u3002\u6027\u5225\u6bd4\u6700\u9ad8<span style=\"word-break: break-all;\" lang=\"EN-US\">(<\/span>\u9010\u6f38\u7537\u591a\u5973\u5c11<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span>\uff0c\u89c0\u5bdf\u6bcd\u89aa\u8207\u6708\u7d93\u521d\u6f6e\u5e74\u9f61<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a014<\/span>\u6b72\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">1.118<\/span>\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">OR<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">1.00<\/span>\u63a7\u5236\uff09\uff0c\u5b83\u9010\u6f38\u4e0b\u964d\uff0c\u76f4\u81f3\u6708\u7d93\u521d\u6f6e\u5e74\u9f61<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a017<\/span>\u6b72<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0[1.000; OR<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">0.89<\/span>\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">0.15-5.26<\/span>\uff09<span style=\"word-break: break-all;\" lang=\"EN-US\">](<\/span>\u7537\u5973\u5e73\u8861<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span>\u3002\u5a66\u5973\u6708\u7d93\u521d\u6f6e\u5e74\u9f61\u5728<span style=\"word-break: break-all;\" lang=\"EN-US\">9<\/span>\u6b72\u81f3<span style=\"word-break: break-all;\" lang=\"EN-US\">11<\/span>\u6b72\uff0c\u751f\u80b2\u7387\u6307\u6578<span style=\"word-break: break-all;\" lang=\"EN-US\">(<\/span>\u80ce\u6578<span style=\"word-break: break-all;\" lang=\"EN-US\">)<\/span>\u4e5f\u5f88\u4f4e\uff0c\u3002<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u7d50\u8ad6<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u5973\u6027\u9032\u5165\u6708\u7d93\u521d\u6f6e\u8d85\u51fa\u6b63\u5e38\u7bc4\u570d\uff0c\u7279\u5225\u662f\u90a3\u4e9b\u6708\u7d93\u521d\u6f6e\u65e9\uff0c\u53ef\u80fd\u6709\u589e\u52a0\u7684\u6a5f\u6703\u751f\u5973\u751f\u3002\u00a0<\/span><\/span><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\"><\/p>\n<p><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; color: red; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">PS:\u00a0<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 14pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u61f7\u5b55\u6642<span style=\"word-break: break-all;\" lang=\"EN-US\">baby<\/span>\u7684\u6027\u5225\u4e00\u76f4\u662f\u6240\u6709\u61f7\u5b55\u592b\u59bb\u6700\u95dc\u5207\u7684\uff0c\u521d\u7d93\u65e9\u591a\u751f\u5973\uff0c\u9019\u4f86\u81ea\u540c\u662f\u9ec3\u7a2e\u4eba\u7684\u65e5\u672c\u7684\u7d71\u8a08\u7814\u7a76\uff0c\u5f88\u6709\u8da3\u3002\u53c3\u8003\u4e4b<span style=\"word-break: break-all;\" lang=\"EN-US\">!<\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><span style=\"word-break: break-all; font-family: Arial;\" lang=\"EN-US\"><br \/><\/span><span style=\"word-break: break-all;\" lang=\"EN-US\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21467205##\" title=\"Human reproduction (Oxford, England).\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Hum Reprod.<\/span><\/a><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">\u00a02011 Jun;26(6):1551-4. Epub 2011 Apr 5.<\/span><\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 13.2pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><strong><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">The sex ratio of offspring is associated with the mothers&#8217; age at menarche.<\/span><\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><span style=\"word-break: break-all;\" lang=\"EN-US\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Fukuda%20M%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Fukuda M<\/span><\/a><span style=\"font-family: 'Times New Roman'; font-size: medium;\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Fukuda%20K%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Fukuda K<\/span><\/a><span style=\"font-family: 'Times New Roman'; font-size: medium;\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Shimizu%20T%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Shimizu T<\/span><\/a><span style=\"font-family: 'Times New Roman'; font-size: medium;\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Nobunaga%20M%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Nobunaga M<\/span><\/a><span style=\"font-family: 'Times New Roman'; font-size: medium;\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Grete%20Byskov%20A%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Grete Byskov A<\/span><\/a><span style=\"font-family: 'Times New Roman'; font-size: medium;\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Yding%20Andersen%20C%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman'; font-size: medium;\">Yding Andersen C<\/span><\/a><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">.<\/span><\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><strong><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">Source<\/span><\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">M&amp;K Health Institute, 30-9 Kariya, Ako, Hyogo 678-0239, Japan .<\/span><\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><strong><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">Abstract<\/span><\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\"><span style=\"font-family: 'Times New Roman';\">BACKGROUND Early menarcheal age is a risk factor for breast and ovarian cancers and is also associated with an increased spontaneous abortion rate. The aim of this study was to investigate whether there is a link between early menarcheal age and the offspring sex ratio. METHODS We recorded the sex of 21208 live born infants, all singletons, born to 10 847 premenopausal women (mean attending age: 37.5 \u00b1 7.2 years, range 22-54) who attended our clinics for obstetrical and gynaecological assessment. We calculated the sex ratio of newborn infants in relation to the mothers&#8217; age of menarche (from 9 to 18 years) and to the number of infants per woman (i.e. fertility index). RESULTS A low offspring sex ratio (males\/females) of 0.800 was observed in mothers who entered menarche at the age of 9 years; the odds ratio (OR) (95% confidence intervals) compared with those of control group with menarche at age 14 was 0.72 (0.29-1.79). The sex ratio remained low, until the group of mothers who entered menarche at 12 years of age [1.009; OR: 0.90 (0.85-0.95)]. The highest sex ratio was observed in mothers with a menarcheal age of 14 years (1.118; OR: 1.00 control) and it gradually decreased until the menarcheal age of 17 years [1.000; OR: 0.89 (0.15-5.26)]. The fertility index was also low in women with menarche at the age of 9 to 11 years. CONCLUSIONS Women entering menarche outside the normal range, especially those with earlier menarche, may have an increased chance of producing female offspring.<\/span><\/span><\/span><\/p>\n<p>\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt 24pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-indent: 0cm;\"><span style=\"font-family: 'Times New Roman';\"><span style=\"word-break: break-all; font-family: Symbol;\" lang=\"EN-US\"><span style=\"word-break: break-all;\"><span style=\"font-size: medium;\"><img border=\"0\" alt=\"*\" width=\"13\" height=\"13\" \/><\/span><span style=\"word-break: break-all; font-size: 7pt; line-height: normal; font-family: 'Times New Roman';\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/span><\/span><\/span><span style=\"word-break: break-all;\" lang=\"EN-US\"><span style=\"font-size: medium;\">\u00a0<\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hum Reprod.\u00a02011 Jun;26(6):1551-4. Epub 2011 Apr 5. (\u6436\u9bae [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1224","post","type-post","status-publish","format-standard","hentry","category-know-how"],"_links":{"self":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1224"}],"version-history":[{"count":0,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1224\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}