{"id":1226,"date":"2018-07-19T18:45:22","date_gmt":"2018-07-19T10:45:22","guid":{"rendered":"http:\/\/baopie.doctor.binflux.com\/2018\/07\/19\/%e6%8f%90%e9%ab%98%e6%b4%bb%e7%94%a2%e7%8e%87\/"},"modified":"2018-07-19T18:45:22","modified_gmt":"2018-07-19T10:45:22","slug":"%e6%8f%90%e9%ab%98%e6%b4%bb%e7%94%a2%e7%8e%87","status":"publish","type":"post","link":"https:\/\/www.becphd.pro\/?p=1226","title":{"rendered":"\u63d0\u9ad8\u6d3b\u7522\u7387"},"content":{"rendered":"<p style=\"margin: 0px; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><img decoding=\"async\" src=\"\/images\/BECFOLDER\/1383095219-1233570087.jpg\" border=\"0\" \/><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\"><span style=\"font-size: medium;\"><strong style=\"font-size: 16px;\"><span style=\"word-break: break-all; color: #7030a0; font-family: \u65b0\u7d30\u660e\u9ad4;\">\u51fa\u8655<\/span><\/strong><strong style=\"font-size: 16px;\"><span style=\"word-break: break-all; color: #7030a0; font-family: Arial;\" lang=\"EN-US\">:<\/span><\/strong><strong style=\"font-size: 16px;\"><span style=\"word-break: break-all; color: #7030a0; font-family: \u65b0\u7d30\u660e\u9ad4;\">\u7b2c\u4e00\u540d\u7684\u4e0d\u5b55\u75c7\u671f\u520a<\/span><\/strong><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; color: #7030a0; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">Hum Reprod Update.\u00a0<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 14pt; color: purple; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">2011<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 14pt; color: purple; font-family: \u6a19\u6977\u9ad4;\">\u5e74<span style=\"word-break: break-all;\" lang=\"EN-US\">7<\/span>\u6708<span style=\"word-break: break-all;\" lang=\"EN-US\">6<\/span>\u65e5<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 14pt; color: purple; font-family: \u6a19\u6977\u9ad4;\">\u00a0<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 14pt; color: purple; font-family: \u6a19\u6977\u9ad4;\">\u6436\u9bae\u7248<\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; color: purple; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\"><br \/><\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa)<\/span>\u7528\u65bc\u8a66\u7ba1\u5b30\u5152\u7642\u7a0b<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u9ec3\u9ad4\u652f\u6301\u4ee5\u63d0\u9ad8\u6d3b\u7522\u7387\u7684\u7cfb\u7d71\u8a55\u50f9\u548c\u7d9c\u6574\u5206\u6790<\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; background-color: #f5f5f5; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU; background-color: #f5f5f5; vertical-align: top; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u4f86\u81ea\u5e0c\u81d8<\/span><span class=\"longtext\" style=\"word-break: break-all;\"><span style=\"word-break: break-all; font-size: 14pt; background-color: white; color: #333333; font-family: \u6a19\u6977\u9ad4; background-position: initial initial; background-repeat: initial initial;\">\u7684\u7814\u7a76<\/span><\/span><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u00a0<span style=\"word-break: break-all; background-color: white; background-position: initial initial; background-repeat: initial initial;\" lang=\"EN-US\"><\/p>\n<p><\/span>\u6458\u8981<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0<br \/><\/span>\u672c\u7cfb\u7d71\u8a55\u50f9\u548c\u7d9c\u6574\u5206\u6790\uff0c\u4ee5\u8a55\u4f30\u662f\u5426\u5c0d<\/span><strong><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa)<\/span><\/span><\/strong><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u7528\u65bc\u9ec3\u9ad4\u652f\u6301<span style=\"word-break: break-all;\" lang=\"EN-US\">ICSI \/ IVF<\/span>\u9031\u671f\u63d0\u9ad8\u6d3b\u7522\u7684\u6982\u7387\u3002\u65b9\u6cd5\u6587\u737b\u6aa2\u7d22\u7cfb\u7d71\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">MEDLINE<\/span>\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">EMBASE<\/span>\uff0c\u4e2d\u592e\u548c\u767b\u8a18<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0RCT<\/span>\uff09\u9032\u884c\uff0c\u4ee5\u78ba\u5b9a\u76f8\u95dc\u7684\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\u7684\u5168\u90e8\u624b\u7a3f\u51fa\u7248\u3002<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0Meta<\/span>\u5206\u6790\u5f97\u51fa\u7684\u6578\u64da\u532f\u96c6\u98a8\u96aa\u5dee\u7570\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">RDS<\/span>\uff09\u548c<span style=\"word-break: break-all;\" lang=\"EN-US\">95<\/span>\uff05\u53ef\u4fe1\u5340\u9593\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">CI<\/span>\uff09\u3002\u96a8\u6a5f\u6548\u61c9\u6a21\u578b\u61c9\u7528\u65bc\u6c60\u7684\u7814\u7a76\u3002\u7d50\u679c\u78ba\u5b9a\u4e86\u516d\u500b\u76f8\u95dc\u96a8\u6a5f\u5c0d\u7167\u8a66\u9a57\u5171\u5305\u62ec<span style=\"word-break: break-all;\" lang=\"EN-US\">2012<\/span>\u7684\u60a3\u8005\u3002\u6982\u7387\u7684\u6d3b\u7522\u7387\uff08<span style=\"word-break: break-all;\" lang=\"EN-US\">RD<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">16<\/span>\uff05\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">95<\/span>\uff05<span style=\"word-break: break-all;\" lang=\"EN-US\">CI<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">+10<\/span>\u81f3<span style=\"word-break: break-all;\" lang=\"EN-US\">+22<\/span>\uff05\uff09\u986f\u8457\u7684\u75c5\u4eba\u63a5\u53d7<\/span><strong><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa)<\/span><\/span><\/strong><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u7684\u9ad8\u65bc\u90a3\u4e9b\u6c92\u6709\u4f7f\u7528\u8005\u3002\u8a72\u5c0f\u7d44\u5206\u6790\u6839\u64da\u985e\u578b\u7684<span style=\"word-break: break-all;\" lang=\"EN-US\">GnRH<\/span>\u985e\u4f3c\u7269\u7528\u65bc<span style=\"word-break: break-all;\" lang=\"EN-US\">\u00a0LH<\/span>\u6291\u5236\u4e26\u6c92\u6709\u6539\u8b8a\u6548\u679c\u89c0\u5bdf\uff08<\/span><strong><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa)<\/span><\/span><\/strong><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u7684\u7814\u7a76\u4e2d\uff0c\u671f\u9593\u4f7f\u7528\u4e86\u5375\u5de2\u523a\u6fc0\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">RD<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">15<\/span>\uff05\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">95<\/span>\uff05<span style=\"word-break: break-all;\" lang=\"EN-US\">CI<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">+5<\/span>\u81f3<span style=\"word-break: break-all;\" lang=\"EN-US\">+23<\/span>\uff05\uff09<span style=\"word-break: break-all;\" lang=\"EN-US\">;<\/span>\u7814\u7a76\u4e2d<span style=\"word-break: break-all;\" lang=\"EN-US\">GnRH<\/span>\u62ee\u6297\u5291\u671f\u9593\u4f7f\u7528\u4e86\u5375\u5de2\u523a\u6fc0\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">RD<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">+19<\/span>\uff05\uff0c<span style=\"word-break: break-all;\" lang=\"EN-US\">95<\/span>\uff05<span style=\"word-break: break-all;\" lang=\"EN-US\">CI<\/span>\uff1a<span style=\"word-break: break-all;\" lang=\"EN-US\">+11<\/span>\u81f3<span style=\"word-break: break-all;\" lang=\"EN-US\">+27<\/span>\uff05\uff09\u3002\u7d50\u8ad6\u73fe\u6709\u7684\u6700\u4f73\u8b49\u64da\u8868\u660e\uff0c<\/span><strong><span style=\"word-break: break-all; font-size: 14pt; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa<\/span><\/span><\/strong><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">)<\/span><span style=\"word-break: break-all; font-size: 14pt; color: #333333; font-family: \u6a19\u6977\u9ad4;\">\u5728\u9ec3\u9ad4\u671f\u986f\u8457\u589e\u52a0\u7684\u6d3b\u7522\u7387\u3002\u00a0<span style=\"word-break: break-all; background-color: white; background-position: initial initial; background-repeat: initial initial;\" lang=\"EN-US\"><br \/><\/span><\/span><\/p>\n<p style=\"margin: 0px; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 19px; list-style: none; word-break: break-all; line-height: 1.5em; background-color: #f5f5f5; vertical-align: top; text-align: justify;\"><span style=\"color: #800000;\"><strong><span style=\"word-break: break-all; font-size: 16pt; background-color: white; color: red; font-family: \u6a19\u6977\u9ad4; background-position: initial initial; background-repeat: initial initial;\" lang=\"EN-US\">PS:\u00a0<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa<\/span><\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">)<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u7684\u89d2\u8272\u591a\u5f69\u591a\u59ff\u3002\u8c50\u5bcc\u4e86\u4eba\u5de5\u751f\u6b96\u7684\u61c9\u7528\u3002<span style=\"word-break: break-all; background-color: white; background-position: initial initial; background-repeat: initial initial;\">\u76ee\u524d<\/span><\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa<\/span><\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">)<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u7528\u65bc\u8abf\u63a7\u523a\u6fc0\u6392\u5375\u524d\u6216\u4e2d\u5c0d\u8166\u4e0b\u5782\u9ad4\u53ca\u5375\u5de2\u7684\u6027\u817a\u8377\u723e\u8499\u7684\u5f71\u97ff\u3002\u4e5f\u7528\u65bc\u53d6\u4ee3\u7834\u5375\u91dd\u65bc<span style=\"word-break: break-all;\" lang=\"EN-US\">PCOS<\/span>\u6216\u9810\u9632<span style=\"word-break: break-all;\" lang=\"EN-US\">OHSS<\/span>\u7684\u529f\u80fd\u3002\u672c\u7bc7\u4ee4\u4eba\u6709\u8208\u8da3\u7684\u662f\u7cfb\u7d71\u6027\u8a55\u50f9\u548c\u7d9c\u6574\u5206\u6790<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e\u6fc0\u7d20\u6fc0\u52d5\u5291\u89f8\u767c<span style=\"word-break: break-all;\" lang=\"EN-US\">(GnRHa<\/span><\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\" lang=\"EN-US\">)<\/span><\/strong><strong><span style=\"word-break: break-all; font-size: 16pt; color: red; font-family: \u6a19\u6977\u9ad4;\">\u7528\u65bc\u53d6\u5375\u6216\u6392\u5375\u4ee5\u5f8c\u7684\u9ec3\u9ad4\u671f,\u662f\u56e0<span style=\"word-break: break-all;\" lang=\"EN-US\">GnRHa<\/span>\u6fc0\u52d5\u5291\u7684\u6a5f\u5236\u5c0d\u80da\u80ce\u548c\u5b50\u5bae\u5167\u819c\u4e5f\u6709\u76f4\u63a5\u5f71\u97ff\u4e14\u6709\u76ca\u5f71\u97ff\u9ec3\u9ad4\u671f\u800c\u589e\u52a0\u6d3b\u7522\u7387\u3002<\/span><\/strong><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 19px; list-style: none; word-break: break-all; line-height: 1.5em; background-color: #f5f5f5; vertical-align: top; text-align: justify;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 21.6pt; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21733980##\" title=\"Human reproduction update.\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Hum Reprod Update.<\/span><\/a><span style=\"font-family: 'Times New Roman';\">\u00a02011 Jul 6. [Epub ahead of print]<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><span style=\"font-family: 'Times New Roman';\">Increased live birth rates with GnRH agonist addition for luteal support in ICSI\/IVF cycles: a systematic review and meta-analysis.<\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Kyrou%20D%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Kyrou D<\/span><\/a><span style=\"font-family: 'Times New Roman';\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Kolibianakis%20EM%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Kolibianakis EM<\/span><\/a><span style=\"font-family: 'Times New Roman';\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Fatemi%20HM%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Fatemi HM<\/span><\/a><span style=\"font-family: 'Times New Roman';\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Tarlatzi%20TB%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Tarlatzi TB<\/span><\/a><span style=\"font-family: 'Times New Roman';\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Devroey%20P%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Devroey P<\/span><\/a><span style=\"font-family: 'Times New Roman';\">,\u00a0<\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Tarlatzis%20BC%22%5BAuthor%5D\" style=\"color: #008db0;\"><span style=\"font-family: 'Times New Roman';\">Tarlatzis BC<\/span><\/a><span style=\"font-family: 'Times New Roman';\">.<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><span style=\"font-family: 'Times New Roman';\">Source<\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><span style=\"font-family: 'Times New Roman';\">Unit for Human Reproduction, Department of Obstetrics and Gynaecology, Medical School, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Nea Efkarpia Peripheral Road, Thessaloniki 54603, Greece.<\/span><\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><strong><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><span style=\"font-family: 'Times New Roman';\">Abstract<\/span><\/span><\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin: 0cm 0cm 0pt; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 19px; color: #000000; font-family: Arial, MingLiU, PMingLiU; text-align: justify;\"><span style=\"word-break: break-all; font-size: 14pt; line-height: 28px;\" lang=\"EN-US\"><span style=\"font-family: 'Times New Roman';\">BACKGROUND The aim of this systematic review and meta-analysis was to evaluate whether the addition of GnRH agonist for luteal support in ICSI\/IVF cycles enhances the probability of live birth. METHODS Systematic literature search (MEDLINE, EMBASE, CENTRAL and RCT registries) was conducted to identify relevant randomized controlled trials published as full manuscripts. Meta-analysis of data yielded pooled risk differences (RDs) and 95% confidence intervals (CIs). A random effects model was applied for pooling the studies. RESULTS Six relevant RCTs were identified including a total of 2012 patients. The probability of live birth rate (RD: +16%, 95% CI: +10 to +22%) was significantly higher in patients who received GnRH agonist support compared with those who did not. The subgroup analysis according to the type of GnRH analogue used for LH suppression did not change the effect observed (studies in which GnRH agonist was used during ovarian stimulation, RD: +15%, 95% CI: +5 to +23%); (studies in which GnRH antagonist was used during ovarian stimulation, RD: +19%, 95% CI: +11 to +27%). CONCLUSIONS The best available evidence suggests that GnRH agonist addition during the luteal phase significantly increases the probability of live birth rates.<\/span><\/span><\/p>\n<p>\u00a0<\/p>\n<p style=\"margin: 0px; padding: 0px 0px 1em; font-size: 13px; list-style: none; word-break: break-all; line-height: 1.5em; color: #000000; font-family: Arial, MingLiU, PMingLiU;\">\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u51fa\u8655:\u7b2c\u4e00\u540d\u7684\u4e0d\u5b55\u75c7\u671f\u520a \u00a0 Hum Reprod Update.\u00a02011\u5e747\u67086\u65e5\u00a0\u6436\u9bae\u7248 \u4fc3\u6027\u817a\u6fc0\u7d20\u91cb\u653e [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1226","post","type-post","status-publish","format-standard","hentry","category-know-how"],"_links":{"self":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1226"}],"version-history":[{"count":0,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=\/wp\/v2\/posts\/1226\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1226"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.becphd.pro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}